服務(wù)熱線
15201163601
-
公司動(dòng)態(tài)NEWS
您當(dāng)前的位置：首頁 > 公司動(dòng)態(tài) > NA12878試劑：揭秘其主要成分與應(yīng)用NA12878試劑：揭秘其主要成分與應(yīng)用
發(fā)布時(shí)間： 2025-02-26 點(diǎn)擊次數(shù)： 1230次在基因組學(xué)研究的廣闊天地中，NA12878試劑以其特殊的優(yōu)勢(shì)和廣泛的應(yīng)用領(lǐng)域，成為了科研人員手中的得力助手。這款試劑的核心成分——來自特定健康個(gè)體的全基因組DNA樣本，不僅具有高度的代表性和穩(wěn)定性，還承載著豐富的遺傳信息，為各類基因組學(xué)研究提供了堅(jiān)實(shí)的基礎(chǔ)。NA12878試劑的主要成分是來自一個(gè)具有北歐和西歐血統(tǒng)的猶他州居民的全基因組DNA。這份DNA樣本經(jīng)過精心提取和純化，確保了其高質(zhì)量和完整性。作為Coriell人類基因組DNA標(biāo)準(zhǔn)品之一，NA12878在基因組測(cè)序、基因突變檢測(cè)、單核苷酸多態(tài)性（SNP）分析等領(lǐng)域展現(xiàn)出了杰出的性能。值得注意的是，該產(chǎn)品中的DNA樣本在CYP2C19基因上存在特定的變異。具體而言，該樣本在CYP2C19基因的外顯子19處存在一個(gè)單次堿基對(duì)（G-to-A）的轉(zhuǎn)變，這一變異導(dǎo)致了異常的剪接位點(diǎn)和截短的蛋白質(zhì)產(chǎn)生。這種截短的蛋白質(zhì)由于缺少血紅素結(jié)合區(qū)而具有催化失活性，為藥物代謝和個(gè)體化用藥研究提供了重要的參考信息。除了CYP2C19基因的變異外，產(chǎn)品中的DNA樣本還包含了人類基因組的完整信息。這使得它成為基因組學(xué)研究、疾病關(guān)聯(lián)分析、遺傳病診斷等領(lǐng)域的理想選擇。科研人員可以利用NA12878試劑進(jìn)行高通量測(cè)序、芯片分析等多種實(shí)驗(yàn)技術(shù)，從而揭示遺傳變異與疾病之間的關(guān)系，為精準(zhǔn)醫(yī)療和個(gè)體化治療提供科學(xué)依據(jù)。
綜上所述，NA12878試劑以其高質(zhì)量的全基因組DNA樣本和特定的基因變異信息，在基因組學(xué)研究領(lǐng)域發(fā)揮著舉足輕重的作用。隨著科技的不斷發(fā)展，它的應(yīng)用前景將更加廣闊，為人類的健康事業(yè)貢獻(xiàn)更多的智慧和力量。
產(chǎn)品中心
Products
-
化學(xué)試劑
Origene parkell pan-biotech PAN lexogen Lampire labtidebiotech laborator labome ABI enzolifesciences emsdiasum EtonBioscience Equitech-bio kirgen invivogen integralmolecular Instech IndoorBiotechnologies INCELL IMMUSMOL G-Biosciences IMMUNOLOGICALS idtdna IMMUNODX ILLUMINA Immunodiagnostics IBALifeSciences Hypoxyprobe Horizon Cygnus Technologies Hellobio Greiner Cell Signaling Glycobiotech Corning FST Evrogen eurofins BioFire Defense biodatacorp atlasantibodies ATCC Astartebio ArcticZymes aobious anshlabs Advanced ChemTech Advaced Cell Diagnostics AdvanDx Agar Scientific ACBR TRc polyscience Fluka Gene Bridges fortebio Biocrick Fisher bioflux biomax beckman AmericanElements MOLTOX Permagen USA Scientific Chemgenes寡核苷酸 Asuragen vmrd抗體 Thermo asusragen AmplideX toxin polyplus signagen Berry&Associates ALZET滲透泵 alzet abcr abvector SGI-DNA Goldbio Iduron Sgidna Chromsystems Coriell GE Chemgenes Matreya Streck VMRD Sigma Cerilliant Innovative Cell Technologies Diagenode Trilinkbiotech Medkoo life diagnostics Gibco Neuromab全國總代 Novus BioLegend Bethyl Toxin Technology Listlabs Seracare 寶利嘉 賽默飛 安迪生物 行業(yè)專用試劑
-
生物試劑
Biosharp Sciex Seahorse Proteintech DiaMag complementtech PeproTech hooke Nzytech Pierce pepnet pelfreez PALL ozbiosciences OXOID ORFLO ommscientific omega nanopore ncbi NexcelomBioscience Mpbio MultiSciences MyBioSource Musechem MiltenyiBiotec minerva-biolabs microspheres-nanospheres microfil microbix modiquestresearch MOBITEC mercodia merckmillipore medicago JPT kerafast Kangchen Malvern magen Kapa Macrocyclics Macherey mabtech Lucigen leica Lifespan lifesensors lifeline life-ilab Lifecore life Licor advancedchemtech Affinity Abgent Abmgood ActiveMotif Acros Acrobiosystems enzymatics epicypher Elastin elabscience Echelon eBioscience eastcoast eaglebio E&K SCIENTIFIC ekfusa duran DSHB Dharmacon DGRC Dako Cypex comptech Encorbio Jetbiofil JCRBcellbank ISOSCIENCES INVIVOCHEM iris-biotech Full Moon BioSystems GBI FormnMax Finescience Favorgen CordenPharma CIL Chromadex Clodronateliposomes Chromogenix Chiron chemservice cellvis cellutron CELLTREAT cellscript cellbiolabs cellecta cedarlane cdnisotopes carbosynth cambio calbioreagents Buchem Boston Cellron Bioworld Biowest Biotium biostatus BiosPacific Biosearch BIOplastics Biooscientific BioPAL Biomol BIOMED Biomatik bioline Biocoat Bioclone Biocision biochain華新康信 biocell Biocare BIAseparations BDpharmingen Baseclick Badrilla B2S Life Sciences Axon Medchem AXIS-SHIELD avivasysbio avidity AVES-LABS Anatrace Americanbio AlphaDiagnoesticInternational Applied Genetics Laboratories Alstem Alomone AcceGen Akina AdvancedBioMatriX Adipogen Accuratechemical Academybiomed Abcam Zymo Research Addexbio ABL Abbexa Aablocks ZeptoMetrix Tocris TAKARA Spherotech Santa Roche Nist PBL MRC Holland rd-biotech Cellgs LC-LAB Greatcell Energy Hyclone Greerlabs GlycoSyn GlycoTech EY laboratories Cayman CanSyn Bioxcell Bio－Rad Agdia Abclonal amsbio auditmicro avantilipids Alsachim HTDialysis jetPRIME Carna Biosciences FItzgerald